Healthy vs. Alzheimer's brain

This image shows a section of one hemisphere of a healthy brain from an older person at left,and a brain with advanced Alzheimer’s disease at right. (UW Medicine Photo)

A $40.5 million collaborative research center headquartered at Seattle’s Allen Institute aims to create high-resolution maps of brains ravaged by Alzheimer’s disease, to trace new paths to early diagnosis and treatment.

The center will draw upon expertise not only at the institute, but also at UW Medicine and Kaiser Permanente Washington Health Research Institute. Funding for the next five years comes from the National Institute on Aging, part of the National Institutes of Health.

Alzheimer’s and other forms of dementia affect 5.8 million Americans, and by 2050, that number is expected to rise to nearly 14 million. It’s the sixth-leading cause of death in the U.S. The Alzheimer’s Association estimates that treating dementia will cost the nation $305 billion this year, and more than $1 trillion in 2050.

Researchers at the Allen Institute have been delving into the neurological roots of dementia for years, but recent developments could accelerate progress.

The new effort will take advantage of techniques that track patterns of gene expression to identify dozens of different types …read more

Source:: GeekWire


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